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Research Publications

Explore our latest scientific contributions and research findings in gastroenterology and nutrition

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The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction

Nature Reviews Gastroenterology & Hepatology; in press (2025)
2025
Research Team: Thompson A, Hughes M, Anastasova S, Conklin L, Thomas T, Leggett C, Faubion W, Miller T, Delaney P, Lacombe L, Loiseau S, Meining A, RichardsKortum R, Tearney G, Kelly P, Yang GZ.
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Novel gastrointestinal tools (GI Tools) for evaluating gut functional capacity in adults with environmental enteropathy in Zambia and Zimbabwe: A crosssectional study protocol

F1000Research
2025
Research Team: Phiri TN, Weatherill JW, MonfordSanchez E, SerranoContreras JI, Melvin C, Kunaka M, Chisenga I, Ngalande P, Mweetwa MN, Besa E, Haider T, Mandal N, Thompson AJ, Edwards CA, Bourke CD, Robertson RC, Posma JM, Banda R, Mwiinga M, Kazhila L, Katsidzira L, BwakuraDangarembizi M, Amadi B, GarciaPerez I, Maitland K, Marchesi JR, Morrison DJ, Frost G, Kelly P.
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An adaptive multiarm randomised trial of biomedical and psychosocial interventions to improve convalescence following severe acute malnutrition in subSaharan Africa: CoSAM trial protocol

BMJ Open
2025
Research Team: BwakuraDangarembizi M, Amadi B, Singa BO, Muyemayema S, Ngosa D, Mwalekwa L, Ngao N, Kazhila L, Mutasa B, Mpofu E, Mudawarima L, Gonzales GB, Mudzingwa S, Mutenda M, Keter LK, Mutasa K, Njunge JM, Jones H, Phiri TN, Mudibo E, Chulu N, Majo FD, Chasekwa B, Tembo A, Nyabinda C, Oduol C, Sauramba V, Tavengwa NV, Langhaug L, Cordani I, Smuk M, Jaki T, Ntozini R, Walson J, Tickell KD, Berkley J, Kelly P, Prendergast AJ; CoSAM Trial Team.
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Environmental enteropathy and inflammatory bowel disease are not mutually exclusive

Digestive and Liver Disease
2025
Research Team: Hodges P, Malambo M, Kawana W, Besa E, Mweetwa M, Kayamba V, Mudenda V, Croft NM, Kelly P.
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Association of intestinal amino acid absorption with uptake of lactulose and rhamnose in adults with environmental enteropathy

American Journal of Tropical Medicine and Hygiene; in press (2025)
2025
Research Team: Shivakumar N, Kashyap S, Morrison DJ, Devi S, Mweetwa MN, Hodges P, Kurpad AV, Kelly P.
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Association of environmental enteropathy with prediabetes and diabetes: a crosssectional study among Tanzanian adults

PLOS ONE
2025
Research Team: PrayGod G, Kweka B, Malindisa E, Rehman AM, FrikkeSchmidt R, Christoffersen C, KroghMadsen R, Friis H, Kelly P, Filteau S.
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Fasting gastric juice melatonin levels in relation to gastroduodenal pathologies among Zambian patients: A crosssectional study

Health Science Reports
2025
Research Team: Sibande J, Hankolwe MN, Kelly P, Kayamba V.
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A metaanalysis of gut microbiome research in malnourished African populations: a natural language processing approach

Philosophical Transactions of the Royal Society B; in press (2025)
2025
Research Team: Mweetwa M, Kelly P, Posma J.
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Associations of prior wasting malnutrition with later indicators of glucose tolerance across four countries in Africa and Asia: the SAMPA cohort study

American Journal of Clinical Nutrition
2025
Research Team: Modoc DP, Ahmed S, Chisenga M, Cox SE, Dasgupta R, Duazo P, FaurholtJepsen D, Kasonka L, Kelly P, Keogh R, Kweka B, KroghMadsen R, Lee N, Malindisa E, Nitsch D, Ngoya P, PrayGod G, Shaw JA, Solon JA, Tembo MJ, TrilokKumar G, Filteau S.
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Small intestinal microbiota in Zambian children with stunting and severe acute malnutrition

Philosophical Transactions of the Royal Society B; in press (2025)
2025
Research Team: Mweetwa MN, Ahsan K, McNulty NP, Besa E, Barratt MJ, Posma JM, Amadi B, Gordon JI, Kelly P.
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The Global Evolution of Inflammatory Bowel Disease across Four Epidemiologic Stages

Nature
2025
Research Team: Hracs L, Windsor JW, Gorospe J, Cummings M, Coward S, Buie MJ, Quan J, Goddard Q, Caplan L, Markovinović A, Williamson T, Abbey Y, Abreu MT, Ali RAR, Abdullah M, Altuwaijri M, Ahuja V, Balderramo D, Banerjee R, Benchimol EI, Bernstein CN, BrunetMas E, Burisch J, Chong VH, Dotan I, Dutta U, El Ouali S, Forbes A, Forss A, Gearry R, Dao VH, Hartono JL, Hilmi I, Hodges P, Jones GR, JuliaoBaños F, Kaibullayeva J, Kelly P, Kobayashi T, Kotze PG, Lakatos PL, Lees C, Limsrivilai J, Lo B, Loftus EV, Ludvigsson JF, Mak JWY, Ng KK, Okabayashi S, Olén O, Panaccione R, Paudel MS, Quaresma AB, Rubin DT, Simadibrata M, Sun Y, Suzuki H, Toro M, Turner D, Vergara BI, Wei SC, YamamotoFurusho JK, Yang SK, Ng SC, Kaplan GG; GIVES21 Research Group.
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Novel gastrointestinal tools (GI Tools) for evaluating gut functional capacity in adults with environmental enteropathy in Zambia and Zimbabwe: A cross-sectional study protocol

F1000Res
2025
Research Team: Phiri TN, Weatherill JW, Monford-Sanchez E, Serrano-Contreras JI, Melvin C, Kunaka M, Chisenga I, Ngalande P, Mweetwa MN, Besa E, Haider T, Mandal N, Thompson AJ, Edwards CA, Bourke CD, Robertson RC, Posma JM, Banda R, Mwiinga M, Kazhila L, Katsidzira L, Bwakura-Dangarembizi M, Amadi B, Garcia-Perez I, Maitland K, Marchesi JR, Morrison DJ, Frost G, Kelly P
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Whole genome sequencing of hepatitis B virus genotypes E and A in Zambia reveals limited viral diversity in HIV coinfection-

Open Forum Infectious Diseases; in press (2025)
2025
Research Team: Vinikoor MJ, Walker A, Nsokolo B, Musonda T, Muula G, Michailidis E, Wandeler G, Alatrakchi N, Kelly P, Le DB, Voges A, Lübke N, Kanunga A, Bosomprah S, Bhattacharya D, Chibundi C, Bwalya G, Musukuma Chifulo K, Suslov A, Feuerherd M, Heim MH, Schwartz RE, Chung RT, Lauer G, Sinkala E, Timm J.
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Intestinal microbiome changes in response to amino acid and micronutrient supplementation: secondary analysis of the AMAZE trial. Gut Microbiome.

Gut Microbiome. 2025;6:e16(1–16). doi:10.1017/gmb.2025.10011.
2025
Research Team: Mweetwa MN, Ahsan K, Louis Auguste J, Besa E, Posma JM, McNulty N, Barrat MJ, Gordon J, Kelly P.
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Prevalence of clarithromycinresistant Helicobacter pylori strains in Zambia: A subSaharan African country

Digestive Diseases
2024
Research Team: Kebotsamang T, Munkombwe D, Bwalya L, Kelly P, Kayamba V.
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Inflammation and CMV viremia during pregnancy drive mortality and shape immune development in HIVexposed infants

Nature Communications
2024
Research Team: Evans C, Mutasa K, Rukobo S, Govha M, Mushayanembwa P, Chasekwa B, Majo FD, Tavengwa NV, Broad J, Noble C, Gough EK, Kelly P, Bourke CD, Humphrey JH, Ntozini R, Prendergast AJ.
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Novel therapies for malnutrition enteropathy in Zambian and Zimbabwean children with severe acute malnutrition: a multiarm phase II trial

Nature Communications
2024
Research Team: Chandwe K, BwakuraDangarembizi M, Amadi B, Tawodzera G, Ngosa D, Dzikiti A, Chulu N, Makuyana R, Zyambo K, Mutasa K, Mulenga C, Besa E, Sturgeon JP, Mudzingwa S, Simunyola B, Kazhila L, Zyambo M, Sonkwe H, Mutasa B, Chipunza M, Sauramba V, Langhaug L, Mudenda V, Murch SH, Hill S, Playford RJ, VanBuskirk K, Prendergast AJ, Kelly P.
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Inflammation and epithelial repair predict mortality, hospital readmission, and growth recovery in children with severe malnutrition

Sci Transl Med
2024
Research Team: Sturgeon JP, Tome J, Dumbura C, Majo FD, Ngosa D, Mutasa K, Zyambo K, Besa E, Chandwe K, Kapoma C, Mwapenya B, Nathoo KJ, Bourke CD, Ntozini R, Chasekwa B, Smuk M, BwakuraDangarembizi M, Amadi B, Kelly P, Prendergast AJ.
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NAD+ precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction

Sci Transl Med
2024
Research Team: Malique A, Sun S, Chandwe K, Amadi B, Haritunians T, Jain U, Muegge BD, Frein J, Sasaki Y, Foster A, Storer CE, Mengesha E, Kern J, McGovern DPB, Head RD, Kelly P, Liu TC.
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New window into hepatitis B in Africa: Liver sampling combined with single-cell omics enables deep and longitudinal assessment of intrahepatic immunity in Zambia

J Infect Dis
2024
Research Team: Musonda T, Wallace MS, Patel H, Martin OP, Oetheimer C, Mwakamui S, Sinkala E, Nsokolo B, Kanunga A, Lauer G, Chung RT, Wandeler G, Bhattacharya D, Kelly P, Alatrakchi N, Vinikoor MJ.
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Multiplexed immunohistochemical evaluation of small bowel inflammatory and epithelial parameters in environmental enteric dysfunction

Am J Clin Nutr
2024
Research Team: VanBuskirk K, Mweetwa M, Kolterman T, Raghavan S, Ahmed T, Ali SA, Khodeza SM, Begum N, Besa E, Denno DM, Jamil Z, Kelly P, Mahfuz M, Moore SR, Mouksassi S, Petri WA, Tarr PI, Sullivan PB, Moskaluk C.
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Enteric pathogens' relationship with small bowel histological features of environmental enteric dysfunction in a multicountry cohort study

Am J Clin Nutr
2024
Research Team: Iqbal NT, Lawrence S, Ahmed T, Chandwe K, Fahim SM, Houpt ER, Kabir F, Kelly P, Liu J, Mahfuz M, Mweetwa M, VanBuskirk K, Tarr PI, Denno DM.
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Histopathology underlying environmental enteric dysfunction in a cohort study of undernourished children in Bangladesh, Pakistan, and Zambia compared with US children

Am J Clin Nutr
2024
Research Team: Kelly P, VanBuskirk K, Coomes D, Mouksassi S, Smith G, Jamil Z, Hossain MS, Syed S, Marie C, Tarr PI, Sullivan PB, Petri WA, Denno DM, Ahmed T, Mahfuz M, Ali SA, Moore SR, Ndao IM, Tearney GJ, Yilmaz OH, Raghavan SS, Moskaluk CA, Liu TC.
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Transcutaneous fluorescence spectroscopy: development and characterisation of a compact, portable, and fiberoptic sensor

J Biomed Opt
2024
Research Team: Monfort Sanchez E, Avery J, Gan J, Qian J, Mandal N, Agarwal A, Mwiinga M, Banda R, Darzi A, Kelly P, Thompson AJ.
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Endoscopic diagnosis of gastric and oesophageal cancer in Lusaka, Zambia: a retrospective analysis

BMC Gastroenterology
2024
Research Team: Kayamba V, Mubbunu M, Kelly P.
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Integrative ‘omics and machinelearningbased image analyses of environmental enteric dysfunction reveal an immunologic and metabolic pathogenesis of intestinal failure.iScience

2024;27:110013
2024
Research Team: Zulqarnain F, Zhao X, Setchell KDR, Sharma Y, Fernandes P, Srivastava A, Ehsan L, Jain V, Raghavan S, Moskaluk C, Haberman Y, Denson LA, Mehta K, Iqbal NT, Rahman N, Sadiq K, Ahmad Z, Idress R, Iqbal J, Ahmed S, Hotwani A, Umrani F, Kelly P, Amadi B, Moore SR, Brown DE, Ali SA, Syed S.
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Associations between dietary patterns and intestinal inflammation among HIVinfected and uninfected adults: A crosssectional study in Tanzania

PLOS ONE
2024
Research Team: Malindisa EK, Dika H, Rehman AM, Kweka B, Todd J, Olsen MF, KroghMadsen R, FrikkeSchmidt R, Friis H, FaurholtJepsen D, Kelly P, Filteau S, PrayGod G.
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Nationwide survey of Helicobacter pylori seropositivity and gastric atrophy in Zambia

Helicobacter
2024
Research Team: Kayamba V, Munshi H, Hankolwe MN, Kavimba CK, Zyambo K, Chongwe G, Knaze, Park JY, Kelly P.
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A crosssectional study of associations between the 13Csucrose breath test, the lactulose rhamnose assay, and growth in children at high risk of environmental enteropathy

Am J Clin Nutr
2024
Research Team: Shivakumar N, Huq S, ParedesOlortegui M, Konyole SO, Devi S, Yazbeck R, Owino VO, Brouwer AF, Kosek MN, Kelly P, Morrison DJ, Lee GO.
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Systemic biological mechanisms underpin poor postdischarge growth among severely wasted children with HIV

Nature Communications
2024
Research Team: Mudibo E, Bogaert J, Tigoi C, Ngari M, Singa B, Lancioni C, Diallo A, Mbale E, Mupere E, Mukisa J, Thitiri J, Timbwa M, Omer E, Ngao N, Musyimi R, Kahindi E, Bamouni R, Bandsma R, Kelly P, Prendergast A, McGrath C, Tickell K, Walson J, Berkley J, Njunge J, Gonzales G.
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Potential determinants of low circulating GLP2 concentrations in Zambian children with nonresponsive stunting

Experimental Physiology
2023
Research Team: Besa EC, Tembo MJ, Mulenga C, Mweetwa M, Choudhry N, Chandwe K, Storer C, Head R, Haritunians T, McGovern D, Amadi B, Kwenda G, Peiris M, Kelly P.
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Development of the global inflammatory bowel disease visualisation of epidemiology studies in the 21st century (GIVES21)

BMC Medical Research Methodology
2023
Research Team: Mak JWY, Sun Y, Limsrivilai J, Abdullah M, Kaibullayeva J, Balderramo D, Vergara BI, Paudel MS, Banerjee R, Hilmi I, Ali RAR, Wei SC, Ng KK, Altuwaijri M, Kelly P, YamamotoFurusho JK, Kotze PG, Ahuja V, Chong VH, Dao HV, Abbey Y, Ching JYL, Ho A, Chan AKW, Bernstein CN, Gearry RB, Abreu M, Rubin DT, Dotan I, Hracs L, Kaplan GG, Ng SC; GIVES21 Consortium.
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Risk factors for inpatient mortality among children with severe acute malnutrition in Zimbabwe and Zambia

European Journal of Clinical Nutrition
2023
Research Team: Sturgeon JP, Mufukari W, Tome J, Dumbura C, Majo FD, Ngosa D, Chandwe K, Kapoma C, Mutasa K, Nathoo KJ, Bourke CD, Ntozini R, BwakuraDangarembizi M, Amadi B, Kelly P, Prendergast AJ; HOPESAM study team.
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Genetic variation in Environmental Enteropathy and stunting in Zambian children: A pilot genome-wide association study using the H3Africa chip

PLOS ONE
2023
Research Team: Mweetwa M, Haritunians T, Dube S, Chandwe K, Amadi B, Zyambo K, Liu TC, McGovern D, Kelly P.
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Severe acute malnutrition promotes bacterial binding over proinflammatory cytokine secretion by circulating innate immune cells

Science Advances
2023
Research Team: Phiri TN, Mutasa K, Rukobo S, Govha M, Mushayanembwa P, Mwakamui S, Haider T, Zyambo K, Dumbura C, Tome J, Runodamoto T, Chidamba L, Majo FD, Ngosa D, Chandwe K, Kapoma C, Mwapenya B, Mufukari W, Sturgeon JP, Robertson RC, Smuk M, Ntozini R, Nathoo K, Amadi B, Kelly P, BwakuraDangarembizi M, Prendergast AJ, Bourke CD.
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Genetic variation in environmental enteropathy and stunting in Zambian children: A pilot genome-wide association study using the H3Africa chip

PLoS ONE
2023
Research Team: Monica N. Mweetwa , Talin Haritunians, Shishir Dube, Kanta Chandwe, Beatrice Amadi, Kanekwa Zyambo, Ta-Chiang Liu, Dermot McGovern, Paul Kelly
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Rapid testing of gut permeability using oral fluorescein and confocal laser endomicroscopy in Zambian adults

Transactions of the Royal Society of Tropical Medicine and Hygiene
2022
Research Team: Mbuki R, Chileya S, Thompson AJ, Kelly P, Kayamba V.
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Contribution of Schistosoma mansoni to systemic inflammation and microbial translocation among persons with HIV in Zambia

Transactions of the Royal Society of Tropical Medicine and Hygiene
2022
Research Team: Furch B, Mwakamui S, Sianongo S, Zyambo K, Heimburger D, Koethe JR, Kelly P.
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Gastrointestinal endoscopy capacity in eastern Africa

Endoscopy International Open
2022
Research Team: Mwachiro M, Topazian HM, Kayamba V, Mulima G, Ogutu E, Erke M, Lenga G, Mutie T, Mukhwana E, Desalegn H, Berhe R, Meshesha BR, Kaimila B, Kelly P, Fleischer D, Dawsey SM, Topazian MD.
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Cryptosporidiosis is predominantly an urban, anthroponotic infectious disease among Zambian children

Transactions of the Royal Society of Tropical Medicine and Hygiene
2022
Research Team: Banda B, Siwila J, Mukubesa AN, Chitanga S, Kaonga P, Changula K, Simulundu E, Saasa N, Kelly P.
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Reduced fractional absorption of zinc in children with environmental enteropathy in Zambia

Journal of Pediatric Gastroenterology and Nutrition
2022
Research Team: Zyambo K, Hodges P, Chandwe K, Mweetwa M, Westcott J, Krebs N, Amadi B, Kelly P.
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Recovery of children following hospitalisation for complicated severe acute malnutrition in Zimbabwe and Zambia

Maternal & Child Nutrition
2022
Research Team: BwakuraDangarembizi M, Dumbura C, Amadi B, Chasekwa B, Ngosa D, Majo FD, Sturgeon JP, Chandwe K, Kapoma C, Bourke CD, Robertson RC, Nathoo KJ, Ntozini R, Norris SA, Kelly P, Prendergast AJ.
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Selenium status in adults and children in Lusaka, Zambia

Heliyon
2022
Research Team: Zyambo K, Hodges P, Chandwe K, Chisenga C, Mayimbo S, Amadi B, Kelly P, Kayamba V.
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Epithelial abnormalities in the small intestine of Zambian children with stunting

Frontiers in Medicine (Gastroenterology)
2022
Research Team: Mulenga C, Sviben S, Chandwe K, Amadi B, Kayamba V, Fitzpatrick JAJ, Mudenda V, Kelly P.
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Singlecell profiling of environmental enteropathy reveals signatures of epithelial remodelling and immune activation

Science Translational Medicine
2022
Research Team: Kummerlowe C, Mwakamui S, Hughes TK, Mulugeta N, Mudenda V, Besa E, Zyambo K, Shay JES, Fleming I, Vukovic M, Doran BA, Aicher TP, Wadsworth MH 2nd, Bramante JT, Uchida AM, Fardoos R, Asowata OE, Herbert N, Yilmaz ÖH, Kløverpris HN, Garber JJ, OrdovasMontañes J, Gartner ZJ, Wallach T, Shalek AK, Kelly P.
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Frontiers in Medicine

2022;9:904339
2022
Research Team: Schillinger RJ, Mwakamui S, Mulenga C, Tembo M, Hodges P, Besa E, Chandwe K, Owino VO, Edwards CA, Kelly P, Morrison DJ.13Csucrose breath test for the noninvasive assessment of environmental enteropathy in Zambian adults.
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Histoblood group antigens, enteropathogen carriage and environmental enteropathy in stunted Zambian children

Journal of Pediatric Gastroenterology and Nutrition
2022
Research Team: Chandwe K, Zyambo K, Mulenga C, Haritunians T, Francois R, Amadi B, Kosek M, Heimburger D, McGovern D, Kelly P.
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Evaluation of an association between gastric cancer and plasma selenium in Zambian adults: a casecontrol study

eCancer Medical Science
2022
Research Team: Zyambo K, Kelly P, Kayamba V.
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Serum antibodies to selected Helicobacter pylori antigens are associated with active gastritis in patients seen at the University Teaching Hospital in Lusaka, Zambia

Malawi Medical Journal
2022
Research Team: Kayamba V, Butt J, Varga M, Shibemba A, Piazuelo M, Wilson K, Zyambo K, Mwakamui S, Mulenga Chola, Waterboer T, Epplein M, Heimburger DC, Atadzhanov M, Kelly P.
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Association between oesophageal cancer and biomass smoke exposure: a casecontrol study.eCancer Medical Science

2022;16:1422
2022
Research Team: Kayamba V, Mulenga C, Mubbunu M, Kazhila L, Hodges P, Kelly P.
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Long-term health after Severe Acute Malnutrition in children and adults – the role of the Pancreas (SAMPA): Protocol

F1000Research
2022
Research Team: Ahmed S, PrayGod G, Lee N, et al.
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Fat and lean mass predict time to hospital readmission or mortality in children treated for complicated severe acute malnutrition in Zimbabwe and Zambia

British Journal of Nutrition
2022
Research Team: BwakuraDangarembizi M, Dumbura C, Amadi B, Singa BO, Ngosa D, Majo FD, Piper JD, Sturgeon JP, Nathoo KJ, Norris S, Chasekwa B, Ntozini R, Wells JC, Kelly P, Prendergast AJ; HOPESAM study team.
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SelfAttentive Adversarial Stain Normalisation

Pattern Recognition
2021
Research Team: Shrivastava A, Adorno W, Sharma Y, Ehsan L, Ali SA, Moore SR, Amadi B, Kelly P, Syed S, Brown DE.
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Reversal of pathogen-induced barrier defects in intestinal epithelial cells by contrapathogenicity agents

Digestive Diseases and Sciences
2021
Research Team: Choudhry N, Scott F, Edgar M, Sanger GJ, Kelly P.
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Safety and ethics in endoscopic studies in children: evidence from the BEECH study in Zambia

Journal of Tropical Paediatrics
2021
Research Team: Chandwe K, Amadi B, Chipunza M, Zyambo M, Kelly P.
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Risk factors for postdischarge mortality following hospitalisation for severe acute malnutrition in Zimbabwe and Zambia

American Journal of Clinical Nutrition
2021
Research Team: BwakuraDangarembizi M, Dumbura C, Amadi B, Ngosa D, Majo FD, Nathoo KJ, Mwakamui S, Mutasa K, Chasekwa B, Norris SA, Ntozini R, Walker AS, Kelly P, Prendergast AJ.
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Artificial Intelligencebased analytics for diagnosis of small bowel enteropathies and black box feature detection

Journal of Pediatric Gastroenterology and Nutrition
2021
Research Team: Syed S, Ehsan L, Shrivastava A, Sengupta S, Khan M, Kowsari K, Guleria S, Sali R, Kant K, Kang SJ, Sadiq K, Iqbal NT, Cheng L, Moskaluk CA, Kelly P, Amadi BC, Ali SA, Moore SR, Brown DE.
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Effect of bovine colostrum with or without egg on in vitro bacterialinduced intestinal damage with relevance for SIBO and infectious diarrhoea

Nutrients
2021
Research Team: Playford RJ, Choudhry N, Kelly P, Marchbank T.
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Adaptation of the small intestine to microbial enteropathogens in Zambian children with stunting

Nature Microbiology
2021
Research Team: Amadi B, Zyambo K, Chandwe K, Besa E, Mulenga C, Mwakamui S, Siyumbwa S, Croft S, Banda R, Chipunza M, Chifunda K, Kazhila L, VanBuskirk K, Kelly P.
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Gene expression profiles compared in environmental and malnutrition enteropathy in Zambian children and adults

EBioMedicine
2021
Research Team: Kelly P, Amadi B, Chandwe K, Besa E, Zyambo K, Chama M, Tarr PI, Shaikh N, Ndao IM, Storer C, Head R.
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Helicobacter pylori infection and hypochlorhydria in Zambian adults and children: a secondary analysis

PLOS ONE
2021
Research Team: Hodges P, Kelly P, Kayamba V.
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Eligibility for hepatitis B antiviral therapy among adults in the general population in Zambia

PLOS ONE
2020
Research Team: Vinikoor M, Sinkala E, Kanunga A, Muchimba M, Zanolini A, Saag M, Pry J, Nsokolo B, Chisenga T, Kelly P.
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Diagnosis of celiac disease and environmental enteropathy on biopsy images using color balancing on Convolutional Neural Networks

In: Proceedings of the Future Technologies Conference (FTC 2019)
2020
Research Team: Kowsari K, Sali R, Khan MN, Adorno W, Ali SA, Moore SR, Amadi BC, Kelly P, Syed S, Brown DE.
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Prevalence of Clostridium difficile and its toxins in hospital patients with diarrhoeal diseases in Lusaka, Zambia

Transactions of the Royal Society of Tropical Medicine and Hygiene
2020
Research Team: Nehanda S, Mulundu G, Kelly P.
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A novel histological index for evaluation of environmental enteric dysfunction identifies geographicspecific features of enteropathy among children with suboptimal growth

PLOS Neglected Tropical Diseases
2020
Research Team: Liu TC, VanBuskirk K, Ali A, Kelly P, Holtz LR, Yilmaz OH, Sadiq K, Iqbal N, Amadi B, Syed S, Ahmed T, Moore S, Ndao IM, Isaacs MH, Pfeifer JD, Atlas H, Tarr PI, Denno DM, Moskaluk CA.
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Glucagon-like peptide 2 concentrations vary in Zambian children during diarrhoea, in malnutrition, and seasonally

Journal of Pediatric Gastroenterology and Nutrition
2020
Research Team: Besa E, Chandwe K, Banda R, Munalula L, Kalomo L, Amadi B, Kelly P.
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Propranolol reduces portal vein diameter in schistosomal liver disease with portal hypertension: a prospective cohort study

American Journal of Tropical Medicine and Hygiene
2020
Research Team: Sinkala E, Vinikoor M, Zyambo K, Besa E, Nsokolo B, Kelly P.
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Biomass smoke is associated with gastric cancer, and probably mediated by oxidative stress and DNA damage: a casecontrol study

Journal of Global Oncology
2020
Research Team: Kayamba V, Zyambo K, Mulenga C, Mwakamui S, Tembo MJ, Shibemba A, Heimburger DC, Atadhanoz M, Kelly P.
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Molecular profiling of gastric cancer in a population with high HIV prevalence reveals a shift to MLH1loss but not the EBV subtype

Cancer Medicine
2020
Research Team: Kayamba V, Butt J, Waterboer T, Besa E, Choudhry N, Hamasuku A, Julius P, Heimburger DC, Atadhzhanov M, Kelly P.
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Hepatosplenic schistosomiasis in Zambian adults is characterized by increased liver stiffness: a nested casecontrol study

Heliyon
2020
Research Team: Sinkala E, Vinikoor M, Siyunda AM, Zyambo K, Besa E, Nsokolo B, Wandeler G, Foster GR, Kelly P.
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Optimisation, validation and field applicability of a 13Csucrose breath test to assess intestinal function in environmental enteropathy among children in resource poor settings: study protocol for a prospective study in Bangladesh, India, Kenya, Jamaica, Peru and Zambia

BMJ Open
2020
Research Team: Lee GO, Schillinger R, Shivakumar N, Whyte S, Huq S, Ochieng Konyole S, Chileshe J, ParedesOlortegui M, Owino V, Yazbeck R, Kosek MN, Kelly P, Morrison D.
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Transcutaneous fluorescence spectroscopy as a tool for noninvasive monitoring of gut function – first clinical experiences

Scientific Reports
2020
Research Team: Maurice J, Lett AM, Skinner C, Lim A, Richardson M, Thomas AP, Summers PA, Vyas K, Tadbier AW, Vilar R, Kuimova MK, Miodragovic S, Vergis N, Kelly P, Cordeiro MF, Hoare J, Darzi A, Goldin R, Thursz M, Thompson AJ.
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Estimated 24hour urinary sodium excretion as a risk factor for oxidative stress in Zambian adults: A crosssectional study

PLOS ONE
2020
Research Team: Kayamba V, Kelly P.
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Health Outcomes, Pathogenesis and Epidemiology of Severe Acute Malnutrition (HOPESAM): rationale and methods of a longitudinal observational study

BMJ Open
2019
Research Team: BwakuraDangarembizi M, Amadi B, Bourke CD, Robertson RC, Mwapenya B, Chandwe K, Kapoma C, Chifunda K, Majo F, Ngosa D, Chakara P, Chulu N, Masimba F, Mapurisa I, Besa E, Mutasa K, Mwakamui S, Runodamoto T, Humphrey JH, Ntozini R, Wells J, Manges AR, Swann J, Walker AS, Nathoo KJ, Kelly P, Prendergast AJ.
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Delayed referral for diagnostic endoscopy is a contributing factor to late gastric cancer diagnosis in Zambia

Health Press Zambia Bulletin
2019
Research Team: Kayamba V, Kelly P.
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HIV related hypochlorhydria does not appear to respond to antiretroviral therapy in Zambian adults: a case control study

Pan African Medical Journal
2019
Research Team: Kayamba V, Shibemba A, Zyambo K, Heimburger DC, Morgan D, Kelly P.
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Effects on body composition and handgrip strength of a nutritional intervention for malnourished HIVinfected adults referred for antiretroviral therapy: a randomised controlled trial

Journal of Nutritional Science
2019
Research Team: PrayGod G, Rehman AM, Wells JCK, Chisenga M, Siame J, Jeremiah K, Kasonka L, Woodd S, Changalucha J, Kelly P, Koethe JR, Heimburger DC, Friis H, Filteau S.
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Assessment of machine learning detection of Environmental Enteropathy and celiac disease in children

JAMA Network Open
2019
Research Team: Syed S, AlBoni M, Khan MN, Sadiq K, Iqbal NT, Moskaluk CA, Kelly P, Amadi B, Ali SA, Moore SR, Brown DE.
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Transcriptomic analysis of enteropathy in Zambian children with severe acute malnutrition

EBioMedicine
2019
Research Team: Chama M, Amadi B, Chandwe K, Besa E, Zyambo K, Shaikh N, Ndao M, Tarr P, Storer C, Head R, Kelly P.
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TAME trial: a multiarm phase 2 randomised trial of four novel interventions for malnutrition enteropathy in Zambia and Zimbabwe; a study protocol

BMJ Open
2019
Research Team: Kelly P, Bell L, Amadi B, BwakuraDangarembizi M, VanBuskirk K, Chandwe K, Chipunza M, Ngosa D, Chulu N, Hill S, Murch S, Playford R, Prendergast AJ.
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Is folate deficiency a common cause of distal symmetric polyneuropathy in Zambian clinics? Journal of the Neurological Sciences

2019;409:116583
2019
Research Team: Kvalsund M, Kayamba V, Kelly P, Birbeck GL, MwansaThurman C, Nyeggen Sommer I, Lamers Y, Gardiner J, Herrmann DN.
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Low IL6, IL10, TNFα and high IL13 cytokine levels are associated with severe hepatic fibrosis in Schistosoma mansoni chronically exposed individuals

Journal of Parasitology Research
2018
Research Team: Mutengo MM, Mduluza T, Kelly P, Mwansa JCL, Kwenda G, Musonda P, Chipeta J.
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High SMAD7 and pSMAD2,3 expression is associated with environmental enteropathy in children

PLOS Neglected Tropical Diseases
2018
Research Team: Syed S, Dinallo V, Iqbal N, Di Iorio L, Di Fusco D, Guleria S, Amadi BC, Sadiq K, Moskaluk C, Ali A, Kelly P, Monteleone G.
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Characterizing the metabolic phenotype of intestinal villus blunting in Zambian children with severe acute malnutrition and persistent diarrhoea

PLOS ONE
2018
Research Team: Farràs M, Chandwe K, MaynerisPerxachs J, Amadi B, LouisAuguste J, Besa E, Zyambo K, Guerrant R, Kelly P, Swann JR.
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Rifaximin reduces markers of inflammation and bacterial 16S rRNA in Zambian adults with hepatosplenic schistosomiasis: a randomised controlled trial

American Journal of Tropical Medicine and Hygiene
2018
Research Team: Sinkala E, Zyambo K, Besa E, Kaonga P, Nsokolo B, Kayamba V, Vinikoor M, Zulu R, Bwalya M, Foster GR, Kelly P.
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Mycobacterium avium lysate induces matrix metalloproteinase1 in intestinal tissue and peripheral blood: observations from selected hospital-based Zambian adults

International Journal of Infectious Diseases
2018
Research Team: Chongwe G, Michelo C, Sinkala E, Kayamba V, Nzaisenga JB, Drobniewski F, Kelly P.
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A sevenyear retrospective review of colonoscopy records from a single centre in Zambia

Malawi Medical Journal
2018
Research Team: Kayamba V, Nicholls K, Morgan C, Kelly P.
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Retinoic acid elicits a coordinated expression of gut homing markers on T lymphocytes of Zambian men receiving oral Vivotif, but not Rotarix, Dukoral or OPVERO vaccines

Vaccine
2018
Research Team: MwanzaLisulo M, Chomba MS, Chama M, Besa EC, Funjika E, Zyambo K, Banda R, Imikendu M, Sianongo S, Hancock REW, Lee A, Chilengi R, Stagg AJ, Namangala B, Kelly P.
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Chronic hepatitis B virus monoinfection at a University hospital in Zambia

World Journal of Hepatology
2018
Research Team: Vinikoor MJ, Sinkala E, Kanunga A, Muchimba M, Nsokolo B, Chilengi R, Wandeler G, Mulenga J, Chisenga T, Bhattacharya D, Saag MS, Foster GR, Fried MW, Kelly P.
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Presence of blood in gastric juice: A sensitive marker for gastric cancer screening in a poor resource setting

PLOS ONE
2018
Research Team: Kayamba V, Zyambo K, Kelly P.
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Diagnostic yield of nontuberculous mycobacteria in patients booked for endoscopy at the University Teaching Hospital, Lusaka

BMC Research Notes
2017
Research Team: Chongwe G, Michelo C, Kelly P.
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Direct biomarkers of microbial translocation correlate with immune activation in adult Zambians with environmental enteropathy and hepatosplenic schistosomiasis

American Journal of Tropical Medicine and Hygiene
2017
Research Team: Kaonga P, Kaimoyo E, Besa E, Zyambo K, Sinkala E, Kelly P.
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Changes in serum phosphate and potassium and their effects on mortality in malnourished African HIVinfected adults starting antiretroviral therapy and given vitamins and minerals in lipidbased nutritional supplements: secondary analysis from the NUSTART trial

British Journal of Nutrition
2017
Research Team: Rehman AM, Woodd SL, Heimburger DC, Koethe JR, Friis H, PrayGod G, Kasonka L, Kelly P, Filteau S.
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Nutritional status is the major factor affecting the grip strength of African HIV patients before and during antiretroviral treatment

Tropical Medicine & International Health
2017
Research Team: Filteau S, PrayGod G, Woodd SL, Friis H, Heimburger DC, Koethe JR, Kelly P, Kasonka L, Rehman AM.
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Impaired barrier function and autoantibody generation in malnutrition enteropathy in Zambia

EBioMedicine
2017
Research Team: Amadi B, Besa E, Zyambo K, Kaonga P, LouisAuguste J, Chandwe K, Tarr PI, Denno DM, Nataro JP, Faubion W, Sailer A, Yeruva S, Brantner T, Murray JA, Prendergast AJ, Turner JR, Kelly P.
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High prevalence of gastric intestinal metaplasia detected by confocal laser endomicroscopy in Zambian adults

PLOS ONE
2017
Research Team: Kayamba V, Shibemba A, Zyambo K, Heimburger D, Morgan D, Kelly P.
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Stage of disease in hepatitis B virus infection in Zambian adults is associated with large cell change but not well defined using classic biomarkers

Transactions of the Royal Society of Tropical Medicine and Hygiene
2017
Research Team: Nsokolo B, Kanunga A, Sinkala E, Zyambo Z, Kumwenda D, Chamab D, Muyinda G, Vinikoor M, Ijaz S, Tedder R, Elmdaah AKA, Jones M, Chiluba C, Mudenda V, Goldin RD, Foster G, Kelly P.
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Effect of an early resuscitation protocol on inhospital mortality among adults with sepsis and hypotension: a randomised clinical trial

JAMA
2017
Research Team: Andrews B, Semmler MW, Muchemwa L, Kelly P, Lakhi S, Heimburger DC, Mabula C, Bwalya M, Bernard GR.
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New insights into Environmental Enteric Dysfunction

Archives of Disease in Childhood
2016
Research Team: Trehan I, Kelly P, Shaikh N, Manary MJ.
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Environmental Enteric Dysfunction and Growth Failure/Stunting in Global Child Health

Pediatrics
2016
Research Team: Owino VO, Ahmed T, Freemark M, Kelly P, Loy A, Manary MJ, Loechl CU.
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Consistency of use and effectiveness of household water treatment practices among urban and rural populations claiming to treat their drinking water at home: a case study in Zambia

American Journal of Tropical Medicine and Hygiene
2016
Research Team: Rosa G, Kelly P, Clasen T.
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Serological response to Epstein–Barr virus early antigen is associated with gastric cancer and Human immunodeficiency virus infection in Zambian adults: a casecontrol study

Pan African Medical Journal
2016
Research Team: Kayamba V, Monze M, Asombang AW, Zyambo K, Kelly P.
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Hepatosplenic schistosomiasis is characterised by high blood markers of translocation, inflammation and fibrosis

Liver International
2016
Research Team: Sinkala E, Kapulu M, Besa E, Zyambo K, Chisoso NJ, Foster GR, Kelly P.
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Oesophagal squamous cell cancer in a highly endemic region

World Journal of Gastroenterology
2016
Research Team: Asombang AW, Kayamba V, Lisulo MM, Trinkaus K, Mudenda V, Sinkala E, Mwanamakondo S, Banda T, Soko R, Kelly P.
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Integration of HIV care into community management of acute childhood malnutrition permits good outcomes: retrospective analysis of three years of a programme in Lusaka

PLOS ONE
2016
Research Team: Amadi B, Imasiku M, Sakala M, Banda R, Kelly P.
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A longitudinal study of systemic inflammation and recovery of lean body mass among malnourished HIVinfected adults starting antiretroviral therapy in Tanzania and Zambia

European Journal of Clinical Nutrition
2016
Research Team: Praygod G, Blevins M, Woodd S, Rehman A, Jeremiah K, Friis H, Kelly P, Changalucha J, Heimburger D, Filteau S, Koethe J.
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T cell subset profile in healthy Zambian adults at the University Teaching Hospital

Pan African Medical Journal
2016
Research Team: Chisenga CC, Kelly P.
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A lactulose, rhamnose assay of intestinal permeability in the assessment of environmental enteric dysfunction

BMJ Global Health
2016
Research Team: Faubion WA, Camilleri MC, Murray JA, Kelly P, Kosek M, Enders F, Larson J, Boe G, Dyer R, Singh R.
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Endomicroscopic and transcriptomic analysis of impaired barrier function and malabsorption in environmental enteropathy

PLOS Neglected Tropical Diseases
2016
Research Team: Kelly P, Besa E, Zyambo K, LouisAuguste J, Lees J, Banda T, Soko R, Banda R, Amadi B, Watson A.
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Lipidbased nutrient supplements containing vitamins and minerals attenuate renal electrolyte loss in HIV/AIDS patients starting antiretroviral therapy: a randomised controlled trial in Zambia

Clinical Nutrition ESPEN
2016
Research Team: Munkombwe D, Mungo TL, Michelo C, Kelly P, Chirwa S, Filteau S.
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Risk factors for mortality among malnourished HIVinfected adults eligible for antiretroviral therapy

BMC Infectious Diseases
2016
Research Team: Woodd SL, Kelly P, Koethe JR, PrayGod G, Rehman AM, Chisenga M, Siame J, Heimburger DC, Friis H, Filteau S.
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Antimicrobial peptide gene expression during oral vaccination: analysis of a randomised controlled trial

Clinical & Experimental Immunology
2016
Research Team: Simuyandi M, Kapulu MC, Kelly P.
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A review of human Selenium requirements, disease and immune function

Medical Journal of Zambia
2015
Research Team: Chisenga CC, Kelly P.
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Potential for use of retinoic acid as an oral vaccine adjuvant

Philosophical Transactions of the Royal Society B
2015
Research Team: MwanzaLisulo M, Kelly P.
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Interactions between intestinal pathogens, enteropathy and malnutrition in developing countries

Current Opinion in Infectious Diseases
2015
Research Team: Prendergast A, Kelly P.
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Appetite testing in HIVinfected African adults recovering from malnutrition and given antiretroviral therapy (ART)

Public Health Nutrition
2015
Research Team: Rehman AM, Chisenga M, Siame J, Sampson G, Woodd S, PrayGod G, Koethe JR, Kelly P, Filteau S.
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Effects on anthropometry and appetite of vitamins and minerals given in lipid nutritional supplements for malnourished HIVinfected adults referred for antiretroviral therapy: results from the NUSTART randomised controlled trial

Journal of Acquired Immune Deficiency Syndromes
2015
Research Team: Rehman AM, Woodd S, PrayGod G, Chisenga M, Siame J, Koethe JR, Heimburger DC, Kelly P, Friis H, Filteau S.
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Effects on mortality of a nutritional intervention for malnourished HIVinfected adults referred for antiretroviral therapy: a randomised controlled trial

BMC Medicine
2015
Research Team: Filteau S, PrayGod G, Kasonka L, Woodd S, Rehman AM, Chisenga M, Siame J, Koethe JR, Changalucha J, Michael D, Kidola J, Manno D, Larke N, Yilma D, Heimburger DC, Friis H, Kelly P.
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HIV infection and domestic smoke exposure, but not human papillomavirus, are risk factors for oesophageal squamous cell carcinoma in Zambia: a casecontrol study

Cancer Medicine
2015
Research Team: Kayamba V, Bateman AC, Asombang A, Shibemba A, Zyambo K, Banda T, Soko R, Kelly P.
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Increased systemic inflammation is associated with cardiac and vascular dysfunction over the first 12 weeks of antiretroviral therapy among undernourished, HIVinfected adults in Southern Africa

Journal of AIDS Clinical Research
2015
Research Team: Bestawros M, Chidumayo T, Blevins M, Canipe A, Bala J, Kelly P, Filteau S, Shepherd BE, Heimburger DC, Koethe JR.
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Tcell subsets predict mortality in malnourished Zambian adults initiating antiretroviral therapy

PLOS ONE
2015
Research Team: Chisenga CC, Filteau S, Siame J, Chisenga M, Prendergast AJ, Kelly P.
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Minimal impact of an ironfortified lipidbased nutrient supplement on haemoglobin and iron status: a randomised controlled trial in malnourished HIVpositive African adults starting antiretroviral therapy

British Journal of Nutrition
2015
Research Team: James P, Friis H, Woodd S, Rehman AM, PrayGod G, Kelly P, Koethe JR, Filteau S.
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Noncommunicable disease in HIV infected adults in Africa: gastrointestinal, hepatic and nutritional disorders

Journal of Acquired Immune Deficiency Syndromes
2014
Research Team: Kelly P, Saloojee H, Chen J, Chung RT.
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Seroepidemiology of Hepatitis E virus infection in an urban population in Zambia: strong association with HIV and environmental enteropathy

Journal of Infectious Diseases
2014
Research Team: Jacobs C, Chiluba C, Phiri C, MwanzaLisulo M, Hill P, Ijaz S, Kelly P.
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High dose multiple micronutrient supplementation improves villous morphology in environmental enteropathy without HIV enteropathy: results from a doubleblind randomised placebo controlled trial in Zambian adults

BMC Gastroenterology
2014
Research Team: LouisAuguste J, Greenwald S, Simuyandi M, Soko R, Banda R, Kelly P.
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Short-term micronutrientantioxidant supplementation has no impact on a serological marker of gastric atrophy in Zambian adults: retrospective analysis of a randomised controlled trial

BMC Gastroenterology
2014
Research Team: Kayamba V, Chomba MS, Kelly P.
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Gastric malignancy survival in Zambia, Southern Africa: A twoyear followup study

Medical Journal of Zambia
2014
Research Team: Asombang A, Kayamba V, TurnerMoss E, Banda L, Colditz G, Mudenda V, Zulu R, Sinkala E, Kelly P.
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Adjuvant potential of low dose alltrans retinoic acid during oral typhoid vaccination in Zambian men

Clinical & Experimental Immunology
2014
Research Team: MwanzaLisulo M, Kapulu MC, Banda R, Sinkala E, Kayamba V, Sianongo S, Kelly P.
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A 12week longitudinal study of microbial translocation and systemic inflammation in undernourished HIVinfected Zambians initiating antiretroviral therapy

BMC Infectious Diseases
2014
Research Team: Canipe A, Chidumayo T, Blevins M, Bestawros M, Bala J, Kelly P, Filteau S, Shepherd BE, Heimburger DC, Koethe JR.
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Improving validity of informed consent for biomedical research in Zambia using a laboratory exposure intervention

PLOS ONE
2014
Research Team: Zulu J, MwansaLisulo M, Besa E, Kaonga P, Chisenga CC, Chomba M, Simuyandi M, Banda R, Kelly P.
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Gastric cancer in Zambian adults: a prospective casecontrol study assessing dietary intake and antioxidant status using isoprostane excretion

American Journal of Clinical Nutrition
2013
Research Team: Asombang AW, Kayamba V, MwanzaLisulo M, Colditz G, Mudenda V, Yarasheki K, Chott R, Rubin D, Gyawali CP, Sinkala E, Mwanamakondo S, AndersonSpearie C, Kelly P.
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Gastric adenocarcinoma in Zambia: a casecontrol study of HIV, lifestyle risk factors, and biomarkers of pathogenesis

South African Medical Journal
2013
Research Team: Kayamba V, Asombang AW, Mudenda V, Lisulo MM, Sinkala E, Mwanamakondo S, Mweemba I, Kelly P.
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Prevalence of schistosome antibodies and hepatosplenic signs and symptoms among patients from Kaoma, Western Province, Zambia

BMC Research Notes
2013
Research Team: Payne L, TurnerMoss E, Mutengo M, Asombang A, Kelly P.
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Followup study to assess the use and performance of household filters in Zambia

American Journal of Tropical Medicine and Hygiene
2013
Research Team: Peletz R, Simuyandi M, Simunyama M, Sarenje K, Kelly P, Clasen T.
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Safety of live, attenuated oral vaccines in HIV infected Zambian adults

Oral vaccines in HIV
2012
Research Team: Banda R, Yambayamba V, Lalusha BD, Sinkala E, Kapulu MC, Kelly P.
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Assessing water filtration and safe storage in households with young children of HIVpositive mothers: a randomised controlled trial in Zambia

PLOS ONE
2012
Research Team: Peletz R, Simunyama M, Sarenje K, Baisley K, Filteau S, Kelly P, Clasen T.
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Intestinal antimicrobial gene expression: impact of micronutrients in malnourished adults during a randomised trial

Journal of Infectious Diseases
2011
Research Team: Dhaliwal W, Shawa T, Khanam M, Jagatiya P, Simuyandi M, Ndulo N, Bevins CL, Sanderson IR, Kelly P.
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A worldwide analysis of betadefensin copy number variation suggests recent selection of a highexpressing DEFB103 gene copy in East Asia

Human Mutation
2011
Research Team: Hardwick RJ, Machado LR, Zuccherato LW, Antolinos S, Xue Y, Shawa N, Gilman RH, Cabrera L, Berg DE, TylerSmith C, Kelly P, TarazonaSantos E, Hollox EJ.
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In a trial of the use of miltefosine to treat HIVrelated cryptosporidiosis in Zambian adults, extreme metabolic disturbances contribute to high mortality

Annals of Tropical Medicine and Parasitology
2011
Research Team: Sinkala E, Katubulushi M, Sianongo S, Obwaller A, Kelly P.
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Differential changes in expression of intestinal antimicrobial peptide genes during Ascaris lumbricoides infection in Zambian adults do not respond to helminth eradication

Journal of Infectious Diseases
2011
Research Team: Kapulu MC, Simuyandi M, Sianongo S, Mutale M, Katubulushi M, Kelly P.
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Interactions between HIV, dietary diversity and socioeconomic position in an urban African setting

Medical Journal of Zambia
2011
Research Team: Harris J, Kelly P, Filteau S.
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Assessing the microbiological performance and potential cost of boiling drinking water in urban Zambia

Environmental Science & Technology
2011
Research Team: Psutka R, Peletz R, Michelo S, Kelly P, Clasen T.
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Drinking water quality, feeding practices and diarrhea among children under 2 years of HIVpositive mothers in periurban Zambia

American Journal of Tropical Medicine and Hygiene
2011
Research Team: Peletz R, Simuyandi M, Sarenje K, Baisley K, Kelly P, Filteau S, Clasen T.
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‘Rumours’ and clinical trials: a retrospective examination of a paediatric malnutrition study in Zambia

BMC Public Health
2010
Research Team: Kingori P, Muchimba M, Sikateyo B, Amadi B, Kelly P.
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Plasma citrulline as a quantitative biomarker of HIVassociated villous atrophy in a tropical enteropathy population

Clinical Nutrition
2010
Research Team: Papadia C, Kelly P, Caini S, Corazza GR, Shawa T, Franze A, Forbes A, Di Sabatino A.
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Gastric and intestinal barrier impairment in tropical enteropathy and HIV: limited impact of micronutrient supplementation during a randomised controlled trial

BMC Gastroenterology
2010
Research Team: Kelly P, Shawa T, Mwanamakondo S, Soko R, Smith G, Barclay GR, Sanderson IR.
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Susceptibility to intestinal infection and diarrhoea in Zambian adults in relation to HIV status and CD4 count

BMC Gastroenterology
2009
Research Team: Kelly P, Todd J, Sianongo S, Mwansa JCL, Sinsungwe H, Katubulushi M, Farthing MJG, Feldman RAF.
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Reduced production of sulfated glycosaminoglycans occurs in Zambian children with kwashiorkor but not marasmus

American Journal of Clinical Nutrition
2009
Research Team: Amadi B, Fagbemi A, Kelly P, Mwiya M, Torrente F, Salvestrini C, Day RM, Golden MH, Eklund E, Freeze HH, Murch SH.
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Changes in serum cytokine concentration after praziquantel treatment in Zambian children with schistosomiasis

Medical Journal of Zambia
2009
Research Team: Shawa TS, Sianongo S, Akokwa I, Mwansa J, Nchito MF, Kelly P.
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Differential effects of Staphylococcal enterotoxin B (SEB)mediated immune activation on constitutive and inducible small intestinal defensins

Clinical & Experimental Immunology
2009
Research Team: Dhaliwal W, Kelly P, BajajElliott M.
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Clinical and ultrasonographic features of abdominal tuberculosis in HIV positive adults in Zambia

BMC Infectious Diseases
2009
Research Team: Sinkala E, Gray S, Zulu I, Mudenda V, Zimba L, Vermund S, Drobniewski F, Kelly P.
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High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial

BMC Infectious Diseases
2009
Research Team: Amadi B, Mwiya M, Sianongo S, Payne L, Watuka A, Katubulushi M, Kelly P.
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Gastrointestinal pathology in the University Teaching Hospital, Lusaka, Zambia – review of endoscopic and pathology records

Transactions of the Royal Society of Tropical Medicine and Hygiene
2008
Research Team: Kelly P, Katema M, Amadi B, Zimba L, Aparicio S, Mudenda V, Baboo KS, Zulu I.
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Inappropriately low aldosterone concentrations in adults with AIDSrelated diarrhoea in Zambia; a study of response to fluid challenge

BMC Research Notes
2008
Research Team: Kaile T, Zulu I, Lumayi R, Ashman N, Kelly P.
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Micronutrient supplementation has a limited effect on intestinal infectious disease and mortality in a Zambian population of mixed HIV status: a cluster randomized trial

American Journal of Clinical Nutrition
2008
Research Team: Kelly P, Katubulushi M, Todd J, Banda R, Yambayamba V, Fwoloshi M, Zulu I, Kafwembe E, Yavwa F, Sanderson IR, Tomkins A.
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Cytokine activation is predictive of mortality in Zambian patients with AIDSrelated diarrhoea

BMC Infectious Diseases
2008
Research Team: Zulu I, Njobvu L, Hassan G, Shawa T, Kelly P.
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Schistosomiasis – a public health problem

Medical Journal of Zambia
2006
Research Team: Shawa ST, Nchito M, Mwansa JCL, Kelly P.
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Interaction between malnutrition and immunity to parasites

Parasite Immunology
2006
Research Team: Hughes S, Kelly P.
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Reduced gene expression of intestinal αdefensins predicts diarrhoea in a cohort of Zambian adults

Journal of Infectious Diseases
2006
Research Team: Kelly P, BajajElliott M, Katubulushi M, Zulu I, Poulsom R, Feldman RA, Bevins CL, Dhaliwal W.
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Intestinal infection before and after nutritional rehabilitation in children recovering from persistent diarrhoea

Medical Journal of Zambia
2006
Research Team: Mwiya M, Amadi B, Kelly P.
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Surviving the impact of HIVrelated illness in the Zambian business sector

AIDS Patient Care and STDs
2003
Research Team: Guinness L, Walker D, Ndubani P, Jama J, Kelly P.
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Escherichia coli enterovirulent phenotypes in Zambians with AIDSrelated diarrhoea

Transactions of the Royal Society of Tropical Medicine and Hygiene
2003
Research Team: Kelly P, Hicks S, Oloya J, Mwansa JCL, Sikakwa L, Zulu I, Phillips AD.
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Intestinal defensin gene expression in human populations

Molecular Immunology
2003
Research Team: Dhaliwal W, BajajElliott M, Kelly P.
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Antimicrobial resistance in enterobacteria from African AIDS patients

Emerging Infectious Diseases
2002
Research Team: Mwansa JCL, Mutela K, Zulu I, Amadi BC, Kelly P.
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Albendazole chemotherapy for AIDSrelated diarrhoea in Zambia – clinical, parasitological and mucosal responses

Alimentary Pharmacology & Therapeutics
2002
Research Team: Zulu I, Veitch A, Sianongo S, McPhail G, Feakins R, Farthing MJG, Kelly P.
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Morbidity and nutritional impairment in relation to CD4 count in a Zambian population with high HIV prevalence

Acta Tropica
2002
Research Team: Kelly P, Zulu I, Amadi B, Munkanta M, Banda J, Rodrigues LC, Mabey D, Feldman R, Farthing MJG.
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Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: a randomised controlled trial

Lancet
2002
Research Team: Amadi BC, Mwiya M, Musuku J, Watuka A, Sianongo S, Ayoub A, Kelly P.
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Lack of evidence for small intestinal mucosal T cell activation as a pathogenic mechanism in African HIVassociated enteropathy

Digestive Diseases and Sciences
2001
Research Team: Veitch AM, Kelly P, Zulu I, McDonald TT, Farthing MJG.
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Vitamin A in HIV infection and AIDS

East African Medical Journal
2001
Research Team: Kafwembe E, Kelly P, Ngalande P.
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A technique for detection of microsporidia adapted for use in developing countries

Transactions of the Royal Society of Tropical Medicine and Hygiene
2001
Research Team: Sianongo S, McDonald V, Kelly P.
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Intestinal and systemic infection, HIV and mortality in Zambian children with persistent diarrhoea and malnutrition

Journal of Pediatric Gastroenterology and Nutrition
2001
Research Team: Amadi BC, Kelly P, Mwiya M, Mulwazi E, Sianongo S, Changwe F, Thomson M, Hachungula J, Watuka A, WalkerSmith JA, Chintu C.
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Helicobacter pylori infection in an urban Zambian population

Journal of Clinical Microbiology
2001
Research Team: Fernando N, Holton J, Zulu I, Vaira D, Mwaba P, Kelly P.
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Impaired bioavailability of vitamin A in adults and children with persistent diarrhoea in Zambia

Alimentary Pharmacology & Therapeutics
2001
Research Team: Kelly P, Musuku J, Kafwembe E, Libby G, Zulu I, Murphy J, Farthing MJG.
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Tropical enteropathy: a T cellmediated crypt hyperplastic enteropathy

European Journal of Gastroenterology & Hepatology
2001
Research Team: Veitch A, Kelly P, Zulu I, Segal I, Farthing MJG.
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HIV and the gut

Int J Gastroenterol
1999
Research Team: Pollok R, Zulu I, Kelly P.
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Micronutrient supplementation for the AIDS diarrhoea-wasting syndrome in Zambia: a randomised controlled trial

AIDS
1999
Research Team: Kelly P, Musonda R, Kafwembe E, Kaetano L, Keane E, Farthing MJG.
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Does sucrase deficiency in black South Africans protect against colonic disease?Lancet

1998;351:183
1998
Research Team: Veitch AM, Kelly P, Segal I, Spies SK, Farthing MJG.
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Local understandings of adult diarrhoeal disease and its treatment in an area of high HIV seroprevalence in Zambia

Trop Med Int Health
1998
Research Team: Ndubani P, Kelly P, Farthing MJG, Wallman S.
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Cryptosporidiosis in urban Zambian children: an analysis of risk factors

Am J Trop Hyg
1998
Research Team: Nchito M, Kelly P, Sianongo S, Luo NP, Feldman RA, Farthing MJG, Baboo KS.
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Plasma leptin in chronic inflammatory bowel disease and HIV: implications for the pathogenesis of anorexia and weight loss

Clin Sci
1998
Research Team: Ballinger A, Kelly P, Hallyburton E, Besser R, Farthing MJG.
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High adult mortality in Lusaka

Lancet
1998
Research Team: Kelly P, Feldman RA, Ndubani P, Baboo KS, Timæus I, Farthing MJG, Wallman S.
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Variable distribution of Cryptosporidium parvum in small and large intestine in AIDS revealed by polymerase chain reaction

Eur J Gastro Hepatol
1998
Research Team: Kelly P, Makumbi FA, Carnaby S, Simjee AE, Luo NP, Farthing MJG.
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Enteropathy in Zambians with HIV related diarrhoea: regression modelling of potential determinants of mucosal damage

Gut
1997
Research Team: Kelly P, Davies SE, Mandanda B, Veitch A, McPhail G, Zulu I, Drobniewski F, Fuchs D, Summerbell C, Luo NP, Pobee JOM, Farthing MJG.
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Cryptosporidiosis in adults in Lusaka, Zambia, and its relationship to oocyst contamination of drinking water

J Infect Dis
1997
Research Team: Kelly P, Nchito M, Baboo KS, Ndubani P, Okeowo NP, Luo NP, Feldman RA, Farthing MJG.
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Prevalence and aetiology of persistent diarrhoea in adults in urban Zambia

Acta Tropica
1996
Research Team: Kelly P, Baboo KS, Woolf M, Ngwenya B, Luo N, Farthing MJG.
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Albendazole chemotherapy for treatment of diarrhoea in patients with AIDS in Zambia: a randomised double blind controlled trial

BMJ
1996
Research Team: Kelly P, Lungu F, Keane E, Baggaley R, Kazembe F, Pobee JOM, Farthing MJG.
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Systemic immune activation as a potential determinant of wasting in Zambians with HIV related diarrhoea

Q J Med
1996
Research Team: Kelly P, Summerbell C, Ngwenya B, Mandanda B, Hosp M, Luo N, Fuchs D, Wachter H, Pobee JOM, Farthing MJG.
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